CSF

Intratumor heterogeneity and T cell exhaustion in primary CNS lymphoma featured image

Intratumor heterogeneity and T cell exhaustion in primary CNS lymphoma

BACKGROUND: Primary central nervous system lymphoma (PCNSL) is a rare lymphoma of the central nervous system, usually of diffuse large B cell phenotype. Stereotactic biopsy …

michael-heming
Cerebrospinal fluid flow cytometry distinguishes psychosis spectrum disorders from differential diagnoses featured image

Cerebrospinal fluid flow cytometry distinguishes psychosis spectrum disorders from differential diagnoses

We performed basic CSF analysis and multi-dimensional flow cytometry of CSF and blood cells from 59 patients with primary psychotic disorders in comparison to inflammatory and …

saskia-rauber
Neurological Manifestations of COVID-19 Feature T Cell Exhaustion and Dedifferentiated Monocytes in Cerebrospinal Fluid featured image

Neurological Manifestations of COVID-19 Feature T Cell Exhaustion and Dedifferentiated Monocytes in Cerebrospinal Fluid

We utilized single-cell sequencing and examined the immune cell profiles from the cerebrospinal fluid of Neuro-COVID patients and discovered an expansion of dedifferentiated …

michael-heming

Leukocyte profiles in blood and CSF distinguish neurosarcoidosis from multiple sclerosis

Distinguishing neurosarcoidosis (NS) from multiple sclerosis (MS) remains challenging and available parameters lack discriminatory power. Comprehensive flow cytometry data of blood …

michael-heming

Integrated single cell analysis of blood and cerebrospinal fluid leukocytes in multiple sclerosis

Cerebrospinal fluid (CSF) protects the central nervous system (CNS) and analyzing CSF aids the diagnosis of CNS diseases, but our understanding of CSF leukocytes remains …

david-schafflick

Immune cell profiling of the cerebrospinal fluid provides pathogenetic insights into inflammatory neuropathies

Objective: Utilize immune cell profiles in the cerebrospinal fluid (CSF) to advance the understanding and potentially support the diagnosis of inflammatory neuropathies. Methods: …

michael-heming